Istamet XR 100/1000 Tablet

• Istamet XR Tablet is used in the treatment of type 2 diabetes
• It is used in addition to diet and exercise to improve blood sugar control in adults with type 2 diabetes

If you experience any persistent or severe side effects, consult your doctor immediately.

• Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Istamet XR Tablet is to be taken with food.

• Istamet XR Tablet is a combination of two antidiabetic medicines: Sitagliptin and Metformin. They help your pancreas produce more insulin, facilitate effective use of insulin by the body, and reduce excess sugar that your liver makes. Together, they provide better control of blood sugar.

• 
  Kidney:

  Istamet XR Tablet should be used with caution in patients with kidney disease. Dose adjustment of Istamet XR Tablet may be needed. Please consult your doctor.Use of Istamet XR Tablet is, however, not recommended in patients with severe kidney disease. Regular monitoring of kidney function test is advisable while you are taking this medicine.

• 
  Liver:

  Istamet XR Tablet is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Istamet XR Tablet may not be needed in these patients. Please consult your doctor.

• 
  Pregnancy:

  Istamet XR Tablet is probably safe to use during pregnancy.Animal studies have shown low or no adverse effect on the foetus, however, there are limited human studies. Please consult your doctor.

• 
  Breastfeeding:

  Istamet XR Tablet is probably safe to use during lactation. Limited human data suggests that the drug does not represent a significant risk to the baby.